Mister Ed (1961)

S1E1 The First Meeting

When Wilbur steps into his barn, he's taken aback to hear his horse speaking to him. Excited yet confused, he rushes to share this astonishing news with his wife and neighbors, but they dismiss him as being out of his mind. Meanwhile, Ed, the horse, insists that he will only converse with Wilbur and refuses to speak to anyone else.